Gel Electrophoresis Reagents and Buffers
ABclonal Technology NOTCH2 Rabbit pAb
This gene encodes a member of the Notch family, a group of Type 1 transmembrane proteins with an extracellular domain containing multiple epidermal growth factor-like (EGF) repeats and an intracellular domain with diverse domains. Notch family proteins regulate developmental processes by controlling cell fate decisions through an evolutionarily conserved intercellular signaling pathway. In Drosophila, Notch interacts with ligands (delta, serrate) to regulate development, and similar ligands have been identified in humans, though their interactions with human Notch proteins are not fully understood. This protein is cleaved in the trans-Golgi network and presented as a heterodimer on the cell surface, acting as a receptor for membrane-bound ligands. It may be involved in vascular, renal, and hepatic development. Two transcript variants encoding different isoforms have been identified.
Biolegend Prime-Step™ Prestained Broad Range Protein Ladder
Prime-Step™ Prestained Broad Range Protein Ladder Apps: WB; Size: 500 uL
Bioworld Sodium Phosphate, 0.1 M, pH 6.8, 1 L
Product DescriptionSodium phosphate buffer has a concentration of 0.1M and a pH of 6.8. It contains 51% of NaH2PO4 (monobasic) and 49% of Na2HPO4 (dibasic). Phosphates have a high buffering capacity and are soluble in water. They inhibit many enzymatic reactions and procedures of molecular cloning. Phosphates also precipitate in ethanol making it impossible to precipitate DNA and RNA from buffers that contain large amounts of phosphate ions.For laboratory use only. Not fit for agricultural, household, clinical use or human consumption.
New England Biolabs, Inc. Quick-Load Purple Low Molecular Weight DNA Ladder – 1.25 ml
Quick-Load Purple Low Molecular Weight DNA Ladder is a pre-mixed, ready-to-load molecular weight marker containing one tracking dye. Tracking dye does not leave a shadow under UV light. The DNA Ladder consists of a proprietary plasmid which is digested to completion with appropriate restriction enzymes to yield 11 bands suitable for use as molecular weight standards for agarose gel electrophoresis. This digested DNA includes fragments ranging from 25-766 base pairs. The 200 base pair band has increased intensity to serve as a reference point.
Bio Rad Laboratories COOMASSIE BRILLIANT BLUE G-250
Coomassie Brilliant Blue G-250 protein stain powder, 10g
ABclonal Technology RBBP8 Rabbit pAb
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
ABclonal Technology MCCC1 Rabbit pAb
This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.